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The prior article in this series presented the traditional treatments for opiates addiction. Suboxone allows a new approach.

Using two separate drugs to shed pounds can be very effective you can find combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it one should err to the side of caution and let the FDA do its job and demand some investigation be done so the public understands the side effects and risks of the medications before we take them. Keep in mind that drug companies are in business to earn money and that they would say everything to keep people on their own medications.

Researchers found that participants investing in this drug for a year, lost excess weight within 4 weeks and have kept the body weight off through the entire 56 weeks from the study. Contrave can be a combination of the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs which are made up of several active ingredient, which might make them more potent and safer.

Combo-pilling is the newest fad or better yet the newest ahead under scrutiny and therefore it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills has become popular may be the fact that by right now there are no long term prescription slimming capsules that have been approved by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be authorized by the FDA.

Seizures can be a side effect with Contrave and must not be taken in those with seizure disorders. The drug could also raise hypertension and heartrate, and shouldn't be used in people with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug.

The FDA also warned that Contrave can raise blood pressure and heartrate and must not be used in patients with uncontrolled high blood pressure level, in addition to by a person with heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients using a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert medical researchers and patients towards the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking.


From a psychiatric perspective, evidence shows that the ordinary neural mechanism for goal-directed behavior has been hijacked by the addiction, and malfunctions so that its ordinary functions are exaggerated and fixated on its object. An object creates a stimulus as well as the person engages in a "goal-directed behavioral response" that creates a "natural high"(Bostwick & Bucci, 2008).